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Present study
|
Sixel-Doring 2014
|
Yoritaka 2009
|
Vibha 2011
|
Romenets 2012
|
Sommerauer 2014
|
Rolinski 2014
|
|---|
|
Patients(n)
|
141
|
158
|
150
|
134
|
98
|
59
|
475
|
|
RCP
|
6
|
no
|
b
|
b
|
no
|
no
|
5
|
|
RBD (%)
|
21.28
|
51.27
|
–
|
19.4
|
–
|
–
|
47.2
|
|
Male pro
|
–
|
–
|
+
|
–
|
+
|
–
|
+
|
|
older
|
–
|
–
|
+
|
–
|
+
|
–
|
–
|
|
MMSE
|
+
|
–
|
–
|
–
|
no
|
no
|
+
|
|
PDSS
|
+
|
no
|
no
|
+
|
no
|
no
|
a
|
|
Depression/anxiety
|
+
|
no
|
no
|
–
|
+
|
no
|
+
|
|
Dementia
|
–
|
no
|
–
|
no
|
ex
|
no
|
+
|
|
Hallucination
|
+
|
no
|
–
|
+
|
–
|
no
|
+
|
|
N-Tremor prominent
|
–
|
–
|
–
|
–
|
+
|
–
|
–
|
|
Axial/limb ratio
|
–
|
–
|
no
|
no
|
–
|
no
|
+
|
|
Constipation
|
+
|
no
|
+
|
no
|
–
|
no
|
+
|
|
Hyposmia
|
–
|
–
|
no
|
no
|
–
|
no
|
–
|
|
OH
|
+
|
no
|
–
|
no
|
+
|
no
|
+
|
|
PSG
|
N
|
Y
|
N
|
N
|
Y
|
Y
|
N
|
- -: no difference, +: significant difference
- Ex: dementia patient was excluded
-
Male pro Male prominent
- No: no data
-
aRolinski use Epworth Sleeping Scale instead of PDSS, difference is significant
-
bYoritaka and Vibha use minimum clinical criteria of ICSD for RBD diagnosis instead
-
N No
-
N-tremor prominent Non-tremor prominent
-
OH Orthostatic hypotension
-
Y Yes
-
RCP RBDSQ cutoff points
- Overall motor symptoms and signs were similar but we found significant difference between the two groups in many aspects of non-motor symptoms, including MMSE performance, visual hallucinations, depression, anxiety, orthostatic hypotension and constipation. Except for constipation, these results are consistent with most previous studies